cbd oil and kidneys

CBD Effects on Kidneys

Posted on August 14th, 2020

Cannabidiol, also known as CBD, has become quite popular. Its popularity has peaked over recent years, with adverts everywhere, from the internet, billboards, television, and even social media. Currently, kidney disease is the ninth most common cause of death in the United States , and things are not getting any better. A common symptom is having physical and emotional pain, that will vary its intensity depending on the patient. Doctors usually prescribe painkillers as a treatment for the pain, but they are usually excreted by the kidneys, which could lead to more kidney damage. With all that it might offer, how could the effects of CBD impact the kidneys?

CBD, according to studies, may be able to help alleviate pain. Early trials of CBD have revealed that it may also help the kidneys due to its potential anti-inflammatory properties, pain management, blood pressure stabilization, and anxiolytic properties. Let’s take a deeper look at the effects of CBD on the kidneys.

What Is CBD and Its Potential Effects on the Kidneys?

Cannabidiol (CBD) is a compound derived from the cannabis plant. Unlike its other counterpart Tetrahydrocannabinol (THC), CBD is non-psychoactive; hence it will not make you high. It might also be a viable option for alleviating aches, symptoms of anxiety, and inflammation. The advantage that CBD may have over other pain medications such as acetaminophen is that the latter is metabolized by the liver and eventually eliminated by the kidneys. They also might damage the cells in the kidney, therefore worsening the condition. CBD, on the other hand, is also metabolized by the liver, but it does not appear to cause any damage to the kidneys, as it is not toxic.

Some of the potential effects of CBD on the kidneys are as follows:

  • Has the potential to help to reduce inflammation in kidneys
  • May help alleviate pain associated with the side effects of the kidney ailments
  • Could help to slow the progression of kidney disease
  • May aid in the prevention of oxidative damage in the kidneys

What Is Kidney Disease?

The kidneys are bean-shaped organs that are situated on either side of the torso. Their primary role is to clean the blood and extract all the excess fluids in the body. The fluids are then removed from the body as urine. They play a crucial role in the filtration of blood in the body. Therefore, the kidneys are crucial to the body, and once they get impaired in their functions, there can be serious implications.

Usually, you can live a long and healthy life without one kidney, so kidney donors and the recipients survive for many years. However, if both of your kidneys fail, then you will be in a traumatizing condition. This is because the condition is fatal; you would need to have a kidney replacement done to survive.

Kidney disease can be acute, and in severe circumstances, become chronic. Below are the different types of kidney disease:

Chronic Kidney Disease

This is the most common form of kidney disease, affecting millions of people all over the world. In fact, most people do not even realize that they have it, which can be quite daunting. Unfortunately, chronic kidney disease does not get any better with time but only worsens. It happens when waste builds up in the body since the kidneys are not working as they should. In the advanced stages, the kidneys may fail altogether, becoming life-threatening. Here, you may need dialysis to remove the excess fluids.


Glomeruli are usually the tiny blood vessels where cleansing of the kidneys take place. This condition is therefore caused by congenital conditions, some drugs, and infections that can make the glomeruli inflamed. The symptoms usually include foamy urine, retention of fluid, and brown or pink urine. The good news is that glomerulonephritis resolves itself with time.

Kidney Stones

The kidneys clean numerous materials from the blood. An example of this is mineral particles. Over time, these minerals crystallize and form kidney stones. Many people are usually able to pass the stones out through urination; however, the process can be quite painful. In severe cases, you may need surgery to remove them.


This is a condition in which the kidneys get inflamed due to bacterial infections. It can damage the kidneys permanently and even be fatal. Symptoms of this condition include fever above 102°F, cloudy urine, painful urination, and pus in the urine. You may also experience nausea and vomiting. It can be treated with antibiotics, and in severe cases, you may need to be hospitalized.

Polycystic Kidney Disease

It is common for the kidney to form cysts or fluid sacs on its surface. Most of them are usually benign and have no severe side effects. Polycystic kidney disease is a genetic condition that will cause the kidneys to grow numerous cysts all over the surface. It can even lead to kidney failure if the cysts interfere with the regular functioning of the kidneys. However, if both of your kidneys fail due to polycystic disease, you might need dialysis.

The Effects of Kidney Disease

Below are some of the effects seen in result to kidney disease:

  • Bleeding disorders
  • Lowered immune function
  • Anemia
  • Heart failure
  • High blood pressure
  • Skin disorders
  • Neurological disorders
  • Acidosis
  • Hypercalcemia
  • Hyperkalemia

Causes of Kidney Disease

On a typical day, the kidneys usually filter around 180 liters of blood . One of the most common causes of kidney disease is diabetes. Diabetes usually leads to high sugar levels that tend to damage the body tissues, including the kidney nephrons. The other most common cause of kidney disease is hypertension. It does this by reducing the blood supply and the autoregulatory sensitivity of the kidneys. Therefore, the nephrons get damaged, causing a strain on the other remaining nephrons, hence increasing their chances of getting damaged. The other causes of kidney disease include:

  • Heart disease
  • Lupus
  • Obesity
  • Smoking
  • Hepatitis B and C

CBD and Kidney Disease: Where Does It Fit?

CBD is not a cure for kidney disease, but how might the effects of CBD impact the kidneys? The body has CB1 and CB2 receptors that help with bodily functions. When you take CBD, it might stimulate the production of natural cannabinoids, which attach themselves to these receptors and help provide a homeostatic balance to the body. Cannabinoids from CBD also interact with these receptors, which is thought to also aid in homeostasis.

The other effect of using CBD is that it might help promote renal function. It has the ability to protect the nephrons from inflammatory and oxidative damage due to its anti-inflammatory properties.

CBD may also promote the normal functioning of the glomerulus. It might also help to prevent the malfunctioning of the body’s filtration mechanisms depending on the type of kidney injury.

Below are ways in which CBD effects may help reduce the symptoms of kidney disease:

Pain Management

CBD is thought to be an analgesic and has been seen to help reduce pain in arthritis and other conditions. CBD enhances the function of the endocannabinoid system (ECS) by blocking the FAAH, a fatty acid used to break down anandamide , and keep more of it in the body. The anandamide binds to the CB1 receptors to help control your pain response. Kidney disease is harrowing, due to the inflammation of the organ, incisional pain from kidney surgery, kidney stones, and even dialysis.

Inflammation Reduction

According to studies, CBD may have anti-inflammatory properties. Since most kidney diseases are usually inflammatory, then CBD might have a positive impact on the inflammatory symptoms. This is done due to its ability to stimulate the endocannabinoid system.

Reduces Nephrotoxicity

The presence of toxins in the renal tissue is known as Nephrotoxicity. These toxins affect the renal function of the kidneys and affect the normal functioning of the organ. CBD might help reduce drug-induced Nephrotoxicity through its relationship with the cannabinoid receptors. This, therefore, may help promote kidney health.

Diabetes Prevention

Diabetes is an inflammatory condition that usually affects the regulation of blood sugar by the body. According to studies, CBD may be able to reduce inflammation. Since diabetes is one of the risk factors of kidney disease, CBD may be able to help.

What Is the Recommended Dosage of CBD?

One of the crucial things that you need to note is that you should talk with your doctor when you want to start taking CBD. This is especially true if you have any health conditions or are taking any medications. CBD can interact with certain medications, so it’s always best to speak with your doctor before starting CBD.

Finding the right dose of CBD may seem daunting, as it affects people differently. Therefore, it is advisable to follow the manufacturer’s instructions and start low and slow. Note how your body is responding and adjust as needed.

Final Word

Kidney disease is a severe condition that can be fatal in severe cases. More research is needed before we fully understand the effects of CBD on kidneys. However, CBD does appear to have several potential benefits. Remember to always consult with your doctor before starting CBD. When looking for the right CBD product for you, search for a trusted and transparent source. Reliable manufacturers will provide third-party lab tests and a certificate of analysis.

Cannabidiol (CBD) may have potential anti-inflammatory and anxiolytic properties. But what are the effects of CBD on kidneys?

CBD Oil and Kidney Disease

Last Updated on September 24, 2020

Over the last few years, the medical uses of cannabis have piqued the curiosity of many Americans. More states are legalizing the use of cannabis for both medical and recreational use, so medical professionals study what benefits it can have on our health.

Over 30 million Americans have some form of chronic kidney disease (CKD). The kidney’s main function is to filter blood, and kidney disease occurs when this process is impaired.

The two primary causes of kidney disease are diabetes and high blood pressure. If left untreated, these conditions can progress to end-stage kidney disease. Patients at this stage either go on dialysis or undergo a kidney transplant.

There are many different medications prescribed to patients with kidney disease. Most of them are diuretics or focus on lowering blood pressure. However, many of these medications don’t help combat the symptoms of kidney disease. They also come with side effects that make them undesirable by the patients.

So what’s the alternative?

A significant number of patients have turned to cannabidiol (CBD) to help treat the symptoms of chronic kidney disease. CBD doesn’t intoxicate its users because it doesn’t contain THC, which is the psychoactive compound found in cannabis.

If you’re looking for a natural alternative for treating kidney disease, CBD oil is worth investigating. However, there’s a lot of confusing information out there about the actual benefits of CBD oil.

This guide will cover everything you need to know about CBD oil and kidney disease.

Table of Contents

What Causes Kidney Disease?

According to the Mayo Clinic, chronic kidney disease occurs when kidney functions gradually deteriorate.

The main job of the kidneys is to filter waste and other unnecessary compounds from the blood. Without our kidneys, toxins would overwhelm our blood and ultimately damage other organs, causing our bodies to shut down.

Early signs of kidney disease are often difficult to detect without a proper examination. Unfortunately, many patients don’t notice they have chronic kidney disease until there has already been noteworthy damage.

Here are some of the common causes of chronic kidney disease:

  • Diabetes (both type 1 & type 2) – Diabetes is when blood glucose levels are higher than normal. Excess glucose can damage blood vessels, which makes them inefficient. As a result, diabetes usually leads to high blood pressure, which can ultimately damage the kidneys, causing kidney disease.
  • High blood pressure – High blood pressure (hypertension) is the number one cause of kidney disease. It can directly damage the filters (the glomeruli) within the kidneys, causing them to malfunction.
  • Glomerulonephritis – Glomeruli are important components of the kidneys. Glomerulonephritis is when the blood vessels within the glomeruli—the kidney’s filtration units—become inflamed or damaged. This damage can lead to chronic kidney disease.
  • Interstitial nephritis – Interstitial nephritis is inflammation around the tubules within the kidney. This inflammation impairs the ability of the kidney to filter waste properly.
  • Polycystic kidney disease – PKD Is a genetic disorder that causes multiple cysts to form within the kidney. The cysts contain fluid, and can grow large enough to interfere with kidney function.
  • Vesicoureteral reflux – In this condition, urine backs up in the kidney tract, leading to inflammation, urinary tract infections, and scarring that can destroy kidney function.

There are many causes of kidney failure, but the two main causes are diabetes and hypertension. The best way to know if you are experiencing kidney disease is to consult your doctor for a thorough examination.

Introducing CBD Oil

CBD oil has skyrocketed in popularity over the last few years. It’s known as a healthy natural alternative to most over-the-counter medicines, and can also treat unpleasant symptoms such as chronic pain, stress, anxiety, and insomnia. But what exactly is CBD oil, and how does it work?

CBD is short for cannabidiol, which is a compound found in the cannabis plant. So, in short, CBD comes from marijuana and hemp. Though CBD comes from marijuana, it doesn’t get you high. CBD a great alternative for those who want to experience the medical benefits of cannabis without THC.

CBD is extracted from hemp plants using carbon dioxide or other methods. After extraction, it’s refined and prepared to be used by the consumer by mixing with a carrier oil that helps to deliver and preserve the extracted CBD. You can purchase CBD either online or in most stores that sell dietary supplements. It’s important only to consume CBD that was extracted safely by a reputable manufacturer.

Now that marijuana is becoming more acceptable in the United States, researchers and medical professionals are starting to recognize CBD as the main therapeutic compound found in cannabis. It’s a versatile substance that comes in many different shapes and forms.

More research is underway on the direct effects CBD has on the body and how it can treat certain symptoms, but CBD oil is already a recommended treatment for several conditions.

When CBD oil enters the body, it reacts with receptors in the endocannabinoid system (ECS), which help regulate pain, sleep, inflammation, and other effects regulated by the nervous system. When ingested through the digestive system, these effects seem amplified. That is why ingesting CBD oil in the form of food or tablets is so popular.

Since the widespread use of CBD oil is relatively new, the exact reasons for its positive effects on the body are still unknown. More research is underway to narrow down how exactly it works in the body and whether it’s a viable long-term solution. Currently, CBD oil should only be used as a supplement to known kidney disease treatments, not as a cure.

There has been some promising research done on CBD oil and kidney disease. While no research has been able to solidify a connection between CBD and kidney receptors, patients have experienced less severe symptoms while taking the natural herbal remedy. CBD has also been proven less harmful to the kidneys than other common drugs such as ibuprofen and aspirin.

How Does CBD Oil Help With Kidney Disease?

Kidney disease is one of the major killers in the United States. It’s deadlier than both breast and prostate cancer. The most alarming aspect of chronic kidney disease is that it’s often undetected until it has already caused significant damage. Some symptoms of kidney disease are low energy, bloody urine, unnatural weight loss, and difficulty breathing.

Due to the developing research on CBD oil and kidney disease, many patients seek out the herbal remedy as a form of treatment. CBD oil is widely known to help treat symptoms such as pain and inflammation, both of which are omnipresent in patients diagnosed with chronic kidney disease. Therefore, if you’re experiencing pain due to chronic kidney disease, CBD oil may help.

Cannabidiol amplifies what our bodies do naturally. As mentioned above, our bodies already have an endocannabinoid mechanism that binds CBD compounds. It primarily works as a neurotransmitter, which signals your brain to alleviate pain and promote relaxation. Naturally, the body might produce endocannabinoids as a mental defense to an injury or a stressful situation.

CBD oil can help relieve pain and anxiety and let your body’s internal systems zero in on the more crucial steps toward recovery. When CBD binds with your cannabinoid receptors, it allows the tissue around the kidney to produce more anandamide, blocking pain. Other compounds found in cannabis such as THC also aid in this process, but CBD specifically does the best job.

To better understand how CBD oil helps treat chronic kidney disease symptoms, let’s first break down different pain receptors. Here is a not-too-technical crash course on how receptors work.

Receptors 101: What are they?

Your brain is a network that transmits and receives information throughout the body. Signals get sent through the nervous system, which is just a complex system made up of billions of cells. Imagine the brain as the control center for the body’s functions and pain receptors as different lookout towers stationed throughout the body.

Whenever there’s damage to organ tissue, such as the kidney, pain receptors send a signal to the brain to initiate a defense. Neurotransmitters like endocannabinoids can regulate these signals, causing them to be less severe. In other words, they make you feel less pain.

The two key receptors for CBD oil are:

CB1 Receptors – Receptors found in the spinal cord, and the brain
CB2 Receptors – Receptors located throughout the body.

It’s no surprise then that many people are looking into CBD oil as a treatment for chronic kidney disease. It’s non-toxic and has fewer long-term effects (if any) on the body compared to other forms of medication.

There are also other benefits of taking CBD oil other than treating CKD. It can also help improve your sleep cycle, decrease anxiety, increase your appetite, and decrease joint inflammation.

Other Benefits of CBD Oil

Research has shown that CBD oil may be a suitable treatment for those with chronic kidney disease. CKD comes with a multitude of symptoms that cause fatigue and discomfort. CBD oil can help combat the symptoms of CKD, allowing patients to be in a more relaxed state as they battle the disease.

Here are some of the additional benefits of taking CBD Oil:

  • Lower anxiety & depression – Battling a disease such as CKD can take a huge toll on your mental health, adding additional stress and fatigue, which is not ideal for a healthy recovery. Studies have shown CBD oil to reduce anxiety and depression in most users.
  • Pain relief – There’s no doubt that the symptoms of CKD can be painful. CBD oil can amplify your body’s natural response to pain. It won’t eliminate the pain, but it’s a much healthier alternative to most pain medications.
  • Increased appetite – When humans are sick, we tend to lose our appetite. Decreased food intake is detrimental because our bodies need food’s energy to recover. CBD oil might increase appetite in certain users. However, there hasn’t been enough research to support this claim.
  • Sleep aid – Insomnia can result from a variety of factors such as anxiety, caffeine consumption, and medications. CBD oil can help treat the main causes of insomnia, improving sleep quality.

Does CBD Oil Have Any Negative Side Effects?

Before undergoing a new form of treatment, it’s important to know that it’s both safe and effective. Modern medicine has blessed us with a wide variety of choices. However, some remedies can do more harm than good. Luckily CBD oil is labeled safe by most medical professionals if it’s extracted safely and consumed responsibly.

Just like any other treatment, CBD oil has guidelines for safe consumption. You have to know the right dose and frequency to take. Though it’s not a deadly substance, there are a few negative side effects of misuse, including:

  • Dry mouth
  • Upset stomach/diarrhea
  • Increased heart rate
  • Groggy headaches
  • Nausea/dizziness
  • Changes in appetite

Taking CBD oil can also offset the effects of other medications. If you’re currently taking medication for CKD, make sure to consult your doctor before trying CBD oil. As mentioned above, CBD oil should be handled as a supplemental treatment, not as a magical cure.

You must purchase your CBD oil from a reputable brand. Since the substance is in such high demand, many “enthusiasts” create homemade oil and sell their products online. Unless you’re sure the CBD oil was extracted in a controlled environment and lab-tested, you should hesitate to buy it.

The negative effects of CBD aren’t severe and often go unnoticed. Compared to other medications that have numerous negative side effects, it’s no surprise that CBD oil is more desirable. However, make sure you consult a healthcare professional to see if you’re suitable for CBD treatment before searching for products.

How to Take CBD Oil

For starters, before you use CBD oil to help treat chronic kidney disease, you need to ask your doctor or check the packaging to determine the correct dosage. Most reputable manufacturers will have dosage guidelines for you to follow. You’ll need to gradually increase your dosage over time to feel the same effects.

CBD oil is a versatile product. There are many ways to consume CBD oil, and that is why it’s so popular. Each method has its unique benefits—it’s all about finding the form most comfortable for you.

Here are some of the most common ways to consume CBD oil:

Edibles – If you’ve been to a health supplement store recently, you may have noticed CBD gummies, cookies, or even lollipops. Edible CBD products, as you may have guessed, are eaten by the user. Though CBD is becoming more accepted across the country, edibles are a less obvious way of using CBD than smoking it.

Be careful when eating CBD edibles, though. They can take up to two hours to kick in. Some people unknowingly eat too much at once and can start to feel sick.

Tinctures and oil– This is by far the most common way to consume CBD oil directly. CBD is mixed with a carrier oil or a small amount of alcohol for absorption through the skin (typically under the tongue). This form is one of the fastest ways to feel the effects of CBD oil.

Topical creams – Did you know that CBD oil can also be a beauty product? You can find many lotions and balms that contain CBD oil, which is applied directly to the skin. In this, “two birds, one stone” scenario, CBD oil can soothe skin and provide medical benefits.

Smoking – Smoking isn’t the healthiest way to consume CBD, but if you already smoke, this might be a suitable method. You can get CBD in the form of flowers and smoke it in a joint, blunt, pipe, or even vaporize it.

Many companies make vape cartridges that contain CBD oil. Vaping is one of the most convenient ways to consume CBD oil. However, THC-containing e-cigarettes have been implicated, but not positively associated with, lung damage in users. The effects might be due to contaminants, carriers, or oils in the vaping solution, and it’s not clear if CBD vaping carries the same potential risk.


Every day, research is discovering more health benefits from CBD oil. For patients experiencing chronic kidney disease, CBD oil can be a healthier alternative to over-the-counter medications. Also, it’s a great way for patients to reap the benefits of cannabis without ingesting THC.

Remember to make sure you’re getting your CBD oil from a trusted source. The best way to know whether or not a manufacturer is reliable is to check their reviews online. Most companies selling high-quality CBD products have a long list of positive reviews from customers.

Another way to determine a company’s credibility is to see how good their customer service is. Good customer service is normally a by-product of a high-quality brand.

Now you have the confidence to start looking into CBD oil as a supplement to treat some of the symptoms of chronic kidney disease.

In Short: FAQ’s related to “CBD Oil and Kidney Disease”

Question: Can you use CBD to help treat kidney disease?
Answer: A significant number of patients have turned to cannabidiol (CBD) to help treat the symptoms of chronic kidney disease. CBD doesn’t intoxicate its users because it doesn’t contain THC, which is the psychoactive compound found in cannabis.

Question: How does CBD work?
Answer: When CBD oil enters the body, it reacts with receptors in the endocannabinoid system (ECS), which help regulate pain, sleep, inflammation, and other effects regulated by the nervous system. When ingested through the digestive system, these effects seem amplified.

Question: How Does CBD Oil Help With Kidney Disease?
Answer: Due to the developing research on CBD oil and kidney disease, many patients seek out the herbal remedy as a form of treatment. CBD oil is widely known to help treat symptoms such as pain and inflammation, both of which are omnipresent in patients diagnosed with chronic kidney disease.

Question: What are the two key receptors in CBD oil?
Answer: CB1 Receptors. Receptors found in the spinal cord, and the brain. Another one is the CB2 Receptors. Receptors located throughout the body.

Question: What are the other benefits you can get in CBD oil besides helping in kidney disease?
Answer: CBD can help anxiety & depression, pain relief, regulate appetite, and can give you a good sleep.

Question: Does CBD Oil Have Any Negative Side Effects?
Answer: Some of the negative side effects of CBD oil includes dry mouth, diarrhea, increased heart rate, headaches.

Question: How do you take CBD oil?
Answer: Some of the common ways to take CBD is through tinctures, topical creams, edibles or gummies, smoking, and supplements.

A significant number of patients have turned to CBD to help treat the symptoms of chronic kidney disease. Find out the benefits of CBD and how can it help! ]]>